Background
Updated: May 2001
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A Case History
What is Aspartame?

Who's Campaigning Against Aspartame?
What's happening in the UK?
Further Facts

Get Active
Books
References

 

A Case History

At the age of 30 months Laura Brewer developed a mysterious rash. GPs suspected it was eczema but as the rash intensified over a 2 week period, Laura's parents started to look for fuller answers. The Brewers received information which led them to believe that aspartame was suspected as a trigger for various illnesses including rashes. Examining the substances Laura regularly consumed they found that aspartame was the sweetener in the fruit squash Laura was drinking. After removing aspartame from Laura's diet they found the rash went away. Then they discovered that many other people were experiencing problems after consuming aspartame, but it was thought that neither the UK Government nor any consumer group was monitoring the situation.

What is Aspartame?

It's a molecule composed of three substances: phenylalanine (50%) aspartic acid (40%); and methyl ester (10%). Phenylalanine and aspartic acid are two of the twenty amino acids found in many of our foods. Methyl ester converts to free methyl alcohol (also known as methanol). There's methyl alcohol in oranges and other fruits, but accompanied by much more ethyl alcohol, the classic antidote.

The UK's Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) reviewed Aspartame in 1992 and noted from a study that: "...it was considered that the ingestion of aspartame by migraine sufferers may cause a significant increase in the frequency of migraine in some subjects."

  1. 1 The patent for aspartame has expired, many companies are now producing this chemical. Disturbingly it has been reported that some of these companies are using genetic engineering within the manufacturing process.
  2. 2 What do we suspect? It is considered that aspartame could be a trigger for many health problems and diseases. In 1995 the United States Department of Health and Human Services recognised 92 different symptoms including headaches, joint pains, rashes, behavioural problems, respiratory and eye problems.
  3. 3. Some researchers believe that chronic illnesses including brain tumours, Multiple Sclerosis and Alzheimer's Disease can either be aggravated or triggered by consumption of aspartame.
  4. 4. Products with aspartame (or other artificial sweeteners): When first put into food and drink in the UK, aspartame and similar sweeteners were almost exclusively restricted to 'diet' type food and drink. Now they're found in many dilutable fruit squashes, soft drinks, diet/'light' carbonated (fizzy) drinks, chewing gum, sweets, crisps, slimming products, yoghurts, breath fresheners, table top sweeteners, powdered hot drinks, jelly, and even vitamin tablets etc.
Who's Campaigning Against Aspartame?

The key campaign group is Mission Possible International founded in 1992 by Mrs Betty Martini in Atlanta, USA. Mission Possible has links with consumer interest groups in almost every country where aspartame is sold.

What's happening in the UK?

Throughout the UK, consumer interest groups are aware of the controversy surrounding aspartame. Many health professionals working within complementary medicine (and the NHS) share concerns over food and drink additives.

ASN(UK) has been specifically established for people who believe that they, family members or friends have been adversely affected by consuming aspartame.

ASN(UK) is concerned that there are people of all ages who are not aware that their conditions may be linked to, and exacerbated, by artificial sweeteners and or other chemical additives. Our immediate objectives are to:

  1. Expand ASN(UK) in order to promote public awareness and alert health professionals of the possible adverse effects associated with chemical additives, in particular artificial sweeteners such as aspartame.
  2. Support individuals who believe they are suffering as a result of / from the effects of ingestion of additives such as aspartame.
  3. Liaise with sympathetic UK consumer interest groups in order to further our objectives.

Our longer term strategies include:

  1. Asking Government to initiate a full independent scientific investigation into aspartame.
  2. Researching the concept of financial compensation where specific chronic conditions can be medically proven to be associated with particular additives.
  3. Consideration of the practicalities of establishing a freely accessible database through which suspected adverse reactions to aspartame (and other chemical additives) can be collated and assessed.
Further Facts

1.      The 'Barcelona Study' found that "aspartame converts to formaldehyde in the bodies of aspartame consumers, and that many of the symptoms reported by victims of aspartame toxicity are indeed those associated with the poisonous and cumulative effects of formaldehyde" 5. This adds weight to fears that aspartame causes brain cancers.

2.      In 1999 research started at King's College, London, funded by The Samantha Dickson Research Trust, looking into possible links between aspartame and increased risk of primary brain tumours.

3.      Testing which resulted in the approval of aspartame is considered by many to be at best flawed. On 29th December 1996 the American TV programme, 60 MINUTES reported on 164 studies which have been conducted into aspartame. ALL of the 74 studies which had been funded by the sweetener industry found no adverse effects. However, 83 of the other 90 studies (conducted by independent laboratories) did find problems.

4.      Phenylketonuria (PKU). In the UK the incidence of PKU is 1:20,000. Phenylketonurics have an extreme sensitivity to the chemical phenylalanine - a component of aspartame. Estimates show that one person in every 60 carries the defective gene responsible for PKU

5.      Babies are tested for PKU sensitivity on day six post-natally (the Scriver Blood Test) which tests not only for PKU but also hypothyroidism (under active thyroid). If the baby is found to be suffering from PKU the parents are given detailed genetic counselling, intensive intervention from a dietician, and close follow up from a paediatric neurologist. A baby suffering from PKU would be severely brain damaged by the age of one year if it was not diagnosed and treated. Once a person is in their teens, medical opinion is that it is no longer necessary for that person to keep to the phenylalanine free diet as the critical phase of brain development has passed. If a woman who has been previously diagnosed as having PKU (a very rare genetic condition) wishes to become pregnant, she receives advice to go on a diet low in phenylalanine, though not as strict as in childhood. There are approximately 2,800 Phenylketonuric people in the UK. ASN(UK) together with other consumer interest organisations, believes that there is a much wider range of people who are at risk as a result of / or from the effects of ingesting aspartame and other additives. Such people could be older individuals, those who are diabetic, pregnant women, those on weight reducing diet as well as children and young people i.e. those who would tend to be the major consumers of food and drink containing artificial sweeteners. It is believed that additive - induced behavioural problems in children could be misdiagnosed (and drugs prescribed) as ADD or ADHD.

6.      Because Phenylketonurics are unable to metabolise phenylalanine all products containing aspartame must by law carry the wording "Contains a source of Phenylalanine"

7.      The World Health Organisation and the European Union have set an Acceptable Daily Intake (ADI) for aspartame at 0-40 mg per kg of body weight per day. Estimates indicate that aspartame is now found in up to 9,000 brands of processed food and drink. Consumer interest groups believe that with aspartame now so widely used in mainstream products, particularly those targeted at children, the ADI is far too high and is in some cases easily exceeded by people, unaware that an ADI exists. The EU has ruled that aspartame should be excluded from the food and drinks of infants and young children

8.      Ironically, this ruling excludes foodstuffs which many youngsters of this age group often consume. The EU defines 'young children' as children aged between one and three years

9.      What can be used instead of artificial sweeteners?

There is a need to wean oneself off additives: reassess shopping habits and look out for different brand names and completely natural products e.g. you can now buy dilutable fruit drinks which are only sweetened with fruit juice. If products contain chemicals, avoid them. It is possible to buy pure juices and concentrates without any sweeteners to dilute with water; desserts can be home made using honey or minimal sugar. Food and drink without chemicals will seem different - give your taste buds time to adjust to them and appreciate the new found flavours. And what's wrong with drinking water? Gradually reduce (and then eliminate) the amount of sweetener in your hot drinks, too - it's a case of re-educating the palate. You can even buy fully natural toothpaste but you'll probably have difficulty finding it in supermarkets - you'll need to go to a specialist health food shop. What to do: Look at the list of ingredients on any processed product you buy. Be warned first of all when reading the label on the front of the packaging. You may see such wording as "No Added Sugar", "Reduced Sugar", "Low Sugar" or "Low Calorie", in which case, the full list of ingredients (on the back) will probably contain aspartame or other artificial sweeteners i.e. sodium saccharin (E954), Acesulfame K (E950) etc. Some products contain more than one artificial sweetener and sugar.

Get Active

1.      If you are avoiding sugar for health reasons please ensure you consult your professional medical advisor before doing anything else. Do not stop taking any medication before seeking professional advice.

2.      Take the 60 day test: Avoid all products containing aspartame (and, if at all possible other artificial sweeteners) for 60 days. After this, note whether various conditions from which you have been suffering such as migraines, headaches joint pain etc. have receded. Please note: You may find you have withdrawal symptoms for a few days e.g. children can crave their "aspartame-laced"drinks and make life difficult for parents.

3.      Return anything containing aspartame to the shop from which you bought it and ask for a refund. Explain that you did not know of the possible effects that chemical additives such as aspartame could have, but you have now become aware and that you may be intolerant such substances.

4.      Write a letter to the shop's head office explaining the action you have taken, ask what their policy is regarding potentially harmful products and mention that you are in correspondence with ASN(UK). Ask them to comment and whether they have received other similar complaints; suggest they consider taking aspartame and other additives such as MSG out of their own brand products. Remind them that Iceland Group plc is doing this. Send a copy of your letter to the manufacturer as well and ask them for their comments.

5.      Write to your local and regional newspapers explaining your experiences. They may well give you some publicity.

6.      The COT Secretariat, Food Standards Agency, Room 651C, Skipton House, Elephant and Castle, LONDON SE1 6LH If the additive you suspect was in a medication please also copy your complaint to The Secretary of State for Health, Richmond House Whitehall LONDON SW1A 2NS Copy your letter to your own MP stating your concerns. Quite a few MPs are already aware of the problems perceived to be associated with aspartame. If your illness goes away or your condition improves after you stop using aspartame, then we suggest that you let your doctor know this in writing, keep a copy and follow up your original complaint to the Secretary of State. NB. There is no overall system for the public to file official medical complaints relating to food products, so we suggest you follow this procedure.

7.      Tell us what you're doing: send us copies of any replies you receive so that we can monitor who is saying what.

Books

There are many books written about adverse reactions to aspartame, amongst those recommended are: "Excitotoxins: The Taste That Kills" by neurosurgeon Russell Blaylock MD, ISBN-929173252.

Aspartame (Nutrasweet ®) Is It Safe?" by H J Roberts MD, ISBN 0-914783-58-0.

Other points to note:

ASN(UK) is concerned about the range of chemicals found in processed foodstuffs e.g. flavour enhancers such as monosodium glutamate also known as MSG (E621), artificial colourings, flavourings and preservatives. We urge readers to eat and drink products which are as natural as possible. Currently we are collecting survivors' stories and news - do write to us. Unless stated otherwise in your correspondence, we will assume that information you send us can be used for publication. We plan to produce ASN(UK) Newsletters 3 times per year.

Please make cheques for £10 payable to ASN UK. Always enclose a SAE to guarantee a reply. Donations are welcome. Please copy and distribute this Fact Sheet. Geoff Brewer B.Sc., M.I.S.M. National Co-ordinator Additives Survivors' Network (UK) 63 Downlands Road DEVIZES SN10 5EF e-mail geoffbrewer@eurobell.co.uk

If you are experiencing health problems, are diabetic etc. do discuss aspartame with your professional medical advisor. Do not stop taking any medication before seeking professional advice.

References:

Statement by the COT on the Safety In Use of Aspartame p.

  1. February 1992. 2 Marie Woolf, The Independent on Sunday No 489, p.1 20 June 1999.
  2. BFDFITE.COUNT Search, symptoms reported against aspartame 8th August 1995. http://www.dorway.com/badnews.html
  3. Fact sheet by H J Roberts, MD, FACPD, FCCP. "Neglected Widespread Emerging Diseases" 1998.
  4. Trocho C et al, Life Sciences, 1998, Vol. 63(5), pp 337-349. Life Sciences a peer reviewed journal, published at www.elsevier.com/ by the Elsevier Organisation. (Known as "The Barcelona Study").
  5. http://wwwlive.who.ch/ncd/hgn/pku.htm
  6. UK Sweeteners in Food Regulations 1995 (SI 1995 No: 3123) Amended: Sweeteners in Food (Amendment) Regulations 1996 (SI 1996 No: 1477) Sweeteners in Food (Amendment) Regulations 1997 (SI 1997 No: 814).
  7. Directive 96/83/EC of the European Parliament and of the Council of 19 December 1996 amending Directive 94/35/EC on sweeteners for use in foodstuffs.
  8. OJ L 48, 19.2.1997, p16. 343393.EN PE 265.957 E-0046/98EN Answer given by Mr Bangemann 19 Feb 98 on the definition.
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